Understanding Protein Flexibility through Dimensionality Reduction
نویسندگان
چکیده
منابع مشابه
Understanding Protein Flexibility through Dimensionality Reduction
This work shows how to decrease the complexity of modeling flexibility in proteins by reducing the number of dimensions necessary to model important macromolecular motions such as the induced-fit process. Induced fit occurs during the binding of a protein to other proteins, nucleic acids, or small molecules (ligands) and is a critical part of protein function. It is now widely accepted that con...
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ژورنال
عنوان ژورنال: Journal of Computational Biology
سال: 2003
ISSN: 1066-5277,1557-8666
DOI: 10.1089/10665270360688228